Enrofloxacin Oral Solution 10%
Each ml contains
Enrofloxacin I.P. 100 mg
Ciprofloxacin interfere with bacterial DNA metabolism by the inhibition of two enzymes, Topoisomerase II (DNA gyrase) and Topoisomerase IV (similar in structure to DNA gyrase).
In Gram-negative organisms such as E.coli DNA gyrase is the primary target, whereas in Gram-positive bacteria such as Staphylococcus aureus Topoisomerase IV is the principle target. This results in breakdown of the DNA, leading to irreversible damage and, finally, to death of the bacterium.
V-FLOXACIN oral solution contains Enrofloxacin, is Bactericidal for gram-negative bacteria, and Mycoplasmas at low concentrations.
V-FLOXACIN administered orally through drinking water exhibits rapid and high oral bioavailability of upto 90% in poultry. Reaches peak plasma concentrations swiftly & maintains effective plasma concentration for a longer duration.
V-FLOXACIN distributes easily into target body compartments e.g. the respiratory tract tissues, at concentrations well above the minimal inhibitory concentrations (MICS).
Intracellular concentrations of V-FLOXACIN exceed those of the extracellular, interstitial fluids and such concentrations activity kill intracellular bacteria such as Mycoplasma & Salmonella.
V-FLOXACIN is a drug of choice in treatment of
- Mycoplasmosis and mixed infections of Mycoplasma and bacteria (CRD)
- Colisepticaemia (E.coli)
- Fowl Cholera (Pasturella)
- Fowl Typhoid (Salmonella)
- Infectious Coryza (Haemophilus)
- Treatment of secondary bacterial infections in viral diseases
Dosage recommendation is at the rate of 10 mg / kg body weight for 3-5 days.
1 ml of solution in 2 litres of water for 3-5 days or as advised by the veterinarian.
V-Floxacin can be combined with anticoccidials regularly used in poultry.
100 ml, 500 ml, 1000 ml, 5000 ml